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TIME Magazine reveals an unprecedented scientific milestone with the birth of Romulus, Remus, and Khaleesi—the first dire wolves to walk the Earth in 12,000 years. These impressive white-coated canids, already weighing 80 pounds at just six months old, display distinctly wild behaviors that set them apart from domestic dogs. Colossal Biosciences achieved this remarkable feat by analyzing ancient DNA from a 13,000-year-old tooth and 72,000-year-old ear skull, then precisely carrying out 20 edits across 14 genes in gray wolf cells. The science behind this breakthrough has far-reaching implications beyond de-extinction, with Colossal simultaneously applying these technologies to save critically endangered species like the red wolf. From their protected 2,000-acre preserve, these pioneering dire wolves represent a powerful new approach in the fight against biodiversity loss. https://time.com/7274542/colossal-dire-wolf/