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Forbes details Colossal Biosciences’ breakthrough in bringing back the dire wolf, marking what the company describes as the world’s first successful de-extinction effort. The article highlights how Colossal extracted DNA from fossilized dire wolf teeth dating back 13,000 and 70,000 years to reconstruct the species’ genome. At five months old, the first two pups—Romulus and Remus—already weigh about 80 pounds each, roughly 25% larger than a gray wolf of the same age, with a third female named Khaleesi born more recently. The animals feature distinctive white coats with slight manes at the shoulders and longer, fox-like tails. They reside in a secure 2,000-acre compound in an undisclosed location. The piece notes Colossal’s impressive roster of investors, including Game of Thrones author George R.R. Martin and stars Sophie Turner and Kit Harrington, and mentions U.S. Interior Secretary Doug Burgum’s positive statement about the potential of de-extinction technology. CEO Ben Lamm explains that this achievement evolved from their work helping preserve critically endangered species like the red wolf, using a less invasive cell-harvesting technique that requires only a simple blood draw. https://www.forbes.com/sites/dbloom/2025/04/08/long-extinct-dire-wolves-are-back-and-not-just-in-game-of-thrones/