May 4, 2026

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Ancient Myth Meets Modern Science: How Colossal Brought the Dire Wolf Back to Life

Complex explores the cultural and scientific story behind one of the most talked-about breakthroughs of the decade

Complex sat down with Colossal Biosciences to unpack the story behind the dire wolf revival, from the ancient DNA extracted from a 72,000-year-old skull to the birth of Romulus, Remus, and Khaleesi. The piece captures how public fascination with the dire wolf, fueled in part by its role in Game of Thrones, has run alongside the rigorous science of CRISPR gene editing and reproductive biology that made their return possible. For CEO Ben Lamm, that intersection is intentional. “The news is just telling us everything that’s wrong, and our only escape is into pop culture,” Lamm told Complex. “But what if you can bridge science, news, and pop culture?” Game of Thrones author and Colossal investor George R.R. Martin put it more simply: “I get the luxury to write about magic, but Ben and Colossal have created magic by bringing these majestic beasts back to our world.”

Read the full feature at Complex.